书目名称 | Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications | 编辑 | Susan C. Frost,Robert McKenna | 视频video | http://file.papertrans.cn/222/221683/221683.mp4 | 概述 | Up to date reference for researchers and students in the carbonic anhydrase family.Contributions from internationally recognized investigators at the forefront of the carbonic anhydrase field.Mix of t | 丛书名称 | Subcellular Biochemistry | 图书封面 |  | 描述 | The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to early studies with a paper in 1948 showing the relationship of 25 different sulfonamides to CA inhibition. It was he who pointed out the importance of both the charged and uncharged character of these compounds for physiological experiments. The field of study that focuses on carbonic anhydrase (CA) has exploded in recent years with the identification of new families and isoforms. The CAs are metalloenzymes which are comprised of 5 structurally different families: the alpha, beta, gamma, and delta, and epsilon classes. The alpha class is found primarily in animals with several isoforms associated with human disease. The beta CAs are expressed primarily in plants and are the most divergent. The gamma CAs are the most ancient. These are structurally related to the beta CAs, but have a mechanism more similar to the alpha CAs. The delta CAs are found in marine algae and diflagellates. The epsilon class is found in prokaryotes in which it is | 出版日期 | Book 2014 | 关键词 | carbonic anhydrase; industrial applications; mechanism; pathology; structure | 版次 | 1 | doi | https://doi.org/10.1007/978-94-007-7359-2 | isbn_softcover | 978-94-024-0250-6 | isbn_ebook | 978-94-007-7359-2Series ISSN 0306-0225 Series E-ISSN 2542-8810 | issn_series | 0306-0225 | copyright | Springer Science+Business Media Dordrecht 2014 |
The information of publication is updating
书目名称Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications影响因子(影响力) 
书目名称Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications影响因子(影响力)学科排名 
书目名称Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications网络公开度 
书目名称Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications网络公开度学科排名 
书目名称Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications被引频次 
书目名称Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications被引频次学科排名 
书目名称Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications年度引用 
书目名称Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications年度引用学科排名 
书目名称Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications读者反馈 
书目名称Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications读者反馈学科排名 
|
|
|