Titlebook: Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications; Susan C. Frost,Robert McKenna Book 2014 Springer

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0306-0225 rs at the forefront of the carbonic anhydrase field.Mix of tThe study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contr

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Structure and Catalytic Mechanism of β-Carbonic Anhydrasesthat produce or utilize CO. or HCO... β-CA is required for normal growth for many organisms. Unique among the five different families of carbonic anhydrases, β-CA is the only family of carbonic anhydrase to exhibit allostery. This chapter summarizes the structure, catalytic mechanism, and allosteric regulation of β-CA.

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978-94-024-0250-6Springer Science+Business Media Dordrecht 2014

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Christian Klein,Jean-Claude Sautsive, as only a few of the lead researchers around the world contributed; it serves only to show that the CA field is still pushing the boundaries of research as it has done since its discovery, and will do for a long time to come.