Titlebook: Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications; Susan C. Frost,Robert McKenna Book 2014 Springer

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Catastrophe Theory and Economic Dynamics,tutively up-regulated in several cancer types and has an important role in tumor progression, acidification and metastasis. High expression of CAIX generally correlates with poor prognosis and is related to a decrease in the disease-free interval following successful therapy. Therefore, it is consid

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Nonlinear Dynamical Systems in Economicsenerated “extrinsically” via mechanisms that regulate the acid–base status of the whole organism; and “intrinsically”, by activity-induced transmembrane fluxes and . generation of acid–base equivalents. The effects of pH changes on neuronal excitability are mediated by diverse, largely synergistical

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Vasile Marinca,Nicolae Herisanuts as molecular probes. Almost all reported carbonic anhydrase inhibitors comprise a zinc binding group in their structure of which the primary sulfonamide moiety (-SO.NH.) is the foremost example and to a lesser extent the primary sulfamate (-O-SO.NH.) and sulfamide (-NH-SO.NH.) groups. Natural pro

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Optimal Parametric Iteration Method,eople and characterized by an elevated intraocular pressure (IOP). At least three isoforms, CA II, IV and XII are targeted by the sulfonamide inhibitors, some of which are clinically used drugs. Acetazolamide, methazolamide and dichlorophenamide are first generation CA inhibitors (CAIs) still used a

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Overview of the Carbonic Anhydrase Familysive, as only a few of the lead researchers around the world contributed; it serves only to show that the CA field is still pushing the boundaries of research as it has done since its discovery, and will do for a long time to come.

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Physiological Functions of the Alpha Class of Carbonic Anhydrasesound in the deepest of branches of the evolutionary tree. Of the five different classes of carbonic anhydrases, the alpha class has perhaps received the most attention because of its role in human pathology. This review focuses on the physiological function of this class of carbonic anhydrases organized by their cellular location.