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Titlebook: Cancer Drug Resistance; Overviews and Method Jose Rueff,António Sebastião Rodrigues Book 2016 Springer Science+Business Media New York 2016

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https://doi.org/10.1007/978-94-009-4636-1ding RNAs (20–22 nt in length) that bind imperfectly to the 3′-untranslated region of target mRNA, has been insistently implicated in several pathological conditions including cancer. Indeed, major hallmarks of cancer, such as cell differentiation, cell proliferation, cell cycle, cell survival, and
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A. Denker,N. Kardjilov,B. Schröder-Smeibidlatients alive 5-years after diagnosis. The therapeutic options for metastatic PDAC have changed in the past few years from single agent gemcitabine treatment to combination regimens. Nowadays, FOLFIRINOX or gemcitabine with nab-paclitaxel are new standard combinations in frontline metastatic setting
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Neutron Activation Autoradiographyis, but also of resistance to therapy. Exosomes are small membrane vesicles of endocytic origin, which contain mRNAs, DNA fragments, and proteins, and are released by many different cell types, including cancer cells. Mounting evidence has shown that cancer-derived exosomes contribute to the recruit
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