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Titlebook: Cancer Drug Resistance; Overviews and Method Jose Rueff,António Sebastião Rodrigues Book 2016 Springer Science+Business Media New York 2016

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Erratum to: In Vitro Methods for Studying the Mechanisms of Resistance to DNA-Damaging Therapeutic
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Neutron Imaging and Applicationseated with TKIs, more cases of resistance are expected and the discovery of biomarkers of resistance acquires a crucial clinical significance..We established a valuable in vitro experimental system that mimics the acquired resistance in the absence of mutations. It was developed by the continuous ex
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Neutron Imaging for the Hydrogen Economyuse of ABCB1-transfected mouse T-lymphoma cell line to study the uptake/efflux of fluorescent probes like ethidium bromide (EB), rhodamine 123 (Rh-123), and carbocyanine dye DiOC., in the presence and absence of potential inhibitors, is currently used in our laboratories to evaluate the ability of a
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M. Arif,D.S. Hussey,D.L. Jacobson, PI3K/AKT/mTOR inhibitors, RAS/RAF/MEK/ERK/MAPK inhibitors, and antiangiogenic drugs. In spite of the many advances in controlling the division of BC cells and the progression of BC tumors these still remain the main cause of death among women in age range of 20–50 years requiring even more efforts
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