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Titlebook: Cancer Drug Resistance; Overviews and Method Jose Rueff,António Sebastião Rodrigues Book 2016 Springer Science+Business Media New York 2016

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发表于 2025-3-21 17:10:44 | 显示全部楼层 |阅读模式
书目名称Cancer Drug Resistance
副标题Overviews and Method
编辑Jose Rueff,António Sebastião Rodrigues
视频videohttp://file.papertrans.cn/222/221095/221095.mp4
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts.Includes supplementary materia
丛书名称Methods in Molecular Biology
图书封面Titlebook: Cancer Drug Resistance; Overviews and Method Jose Rueff,António Sebastião Rodrigues Book 2016 Springer Science+Business Media New York 2016
描述.This volume discusses the latest advancements and technologies used in cancer drug resistance research. .Cancer Drug Resistance: Overviews and Methods .contains chapters that cover topics such as: studying the mechanics of resistance to DNA damaging therapeutic drugs; studies to delineate the role of efflux transporters; expression of drug transporters; resistance to targeted therapies in breast cancer; the role of microRNAs in current pancreatic cancer treatment; and cancer exosomes as mediators of drug resistance or clinical and molecular methods in drug development and the use of bioinformatics in the management of cancer drug resistance data. Written in the highly successful .Methods in Molecular Biology .series format, chapters include overviews of the main issues in cancer drug resistance and the respective mechanisms, as well as introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.. . Authoritative and practical, .Cancer Drug Resistance: Overviews and Methods,. is a valuable resource to researchers, oncobiologists and clinical
出版日期Book 2016
关键词cellular resistance; multi-drug resistance (MDR); DNA; chemotherapy; adenosine5‘-triphosphate (ATP); bind
版次1
doihttps://doi.org/10.1007/978-1-4939-3347-1
isbn_softcover978-1-4939-8027-7
isbn_ebook978-1-4939-3347-1Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media New York 2016
The information of publication is updating

书目名称Cancer Drug Resistance影响因子(影响力)




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书目名称Cancer Drug Resistance年度引用




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书目名称Cancer Drug Resistance读者反馈




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Cancer Drug Resistance978-1-4939-3347-1Series ISSN 1064-3745 Series E-ISSN 1940-6029
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Yu. A. Izyumov,V. E. Naish,R. P. Ozerovthe patient’s genetic makeup or be acquired by tumors that are initially sensitive to cancer drugs. All in all, it may be responsible for treatment failure in over 90 % of patients with metastatic cancer. Cancer drug resistance, in particular acquired resistance, may stem from the micro-clonality/mi
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https://doi.org/10.1007/978-0-387-78693-3cquire multidrug resistance (MDR) and no longer respond to chemotherapy. Efflux transporters play a predominant role in mediating MDR. Cellular accumulation (uptake) and permeability studies serve as invaluable methods to detect drug efflux/transport mechanism. These methods are generally performed
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Neutron Imaging for the Hydrogen Economyporters, and has been associated with drug resistance in eukaryotic cells. Multidrug resistance (MDR) is related to an increased expression and function of the ABCB1 (P-gp) efflux pump that often causes chemotherapeutic failure in cancer. Modulators of this efflux pump, such as the calcium channel b
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