Titlebook: CCN proteins in health and disease; An overview of the F Annick Perbal,Masaharu Takigawa,Bernard Perbal Book 2010 Springer Science+Business

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Asking the Right Questions: What Can the Structure of the CCN Protein Domains Tell Us?, a CT domain. These domains give a broad repertoire of functions to the CCN family including angiogenesis, skeletal development tumourigenesis, wound healing, cell proliferation, adhesion and survival. These wide variety of biological functions are enabled due to the multi-domain nature of the prote

Orchiectomy

Nucleophosmin/B23: A Multifunctional Regulator that Determines the Fate of , mRNA, of . is tightly regulated to confer a maximal level at prehypertrophic – hypertrophic stages, in which the 3‘-untranslated region (UTR) of the mRNA is critically involved in mediating its post-transcriptional regulation. In our previous studies, we found that a 40-kDa protein binding specifically t

obeisance

,The CCN Genes as the “Master” Regulators of Angiogenesis, Vasculogenesis, Fibrogenesis and Cell Difand pathological states and for engineering functional tissue constructs in vitro. Similarly, embryonic and fetal development of a variety of tissues is, at least in part, orchestrated by mechanical cues although such influence is seldom acknowledged because it is difficult to elaborate experimental

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Role of Connective Tissue Growth Factor in Cardiac Fibrosis,triggered by a number of signaling pathways that result in excessive production and deposition of extracellular matrix (ECM). Connective Tissue Growth factor (CTGF, CCN2), a member of CCN (.yr61, .tgf, .ov) family, is a multifunctional protein that is expressed in both cardiac myocytes and fibroblas

最有利

Gene Expression of CCN Family Members in Young and Aged Human Skin In Vivo,tracellular matrix production. Altered expression of CCN family members are associated with several pathological states, including tissue fibrosis, inflammation, and cancer. We have previously reported that CCN1 and CCN2 are predominantly expressed in dermal fibroblasts, and are involved in aberrant