Titlebook: CCN proteins in health and disease; An overview of the F Annick Perbal,Masaharu Takigawa,Bernard Perbal Book 2010 Springer Science+Business

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Annick Perbal,Masaharu Takigawa,Bernard PerbalUnique book volume on the 2008 CCN SOciety Conference

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,The CCN Genes as the “Master” Regulators of Angiogenesis, Vasculogenesis, Fibrogenesis and Cell Difthat regulate the expression of numerous fetal genes including a subset of inducible ECM-associated proteins referred to as Cysteine-rich protein 61 (Cyr61 or CCN1) and connective tissue growth factor (CTGF or CCN2). CCN1 and CCN2 are structurally-related and functionally multifaceted multimodular p

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A Monoclonal Antibody Approach to CCN5 Domain Analysis,ions of individual domains of CCN5, we are developing domain-specific mouse monoclonal antibodies. Monoclonal antibodies have the advantages of great specificity, reproducibility, and ease of long-term storage and production. In this communication, we injected mixtures of GST-fused rat CCN5 domains

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Role of Connective Tissue Growth Factor in Cardiac Fibrosis,ad. Recently, we have shown that KLF15 is a novel negative regulator of CTGF expression in the heart via its ability to counteract Smad signaling at the CTGF promoter. From a clinical standpoint, progress has been made in utilizing CTGF levels as a biomarker for fibrotic diseases. In this chapter, w