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Titlebook: Buruli Ulcer; Mycobacterium Ulcera Gerd Pluschke,Katharina Röltgen Book‘‘‘‘‘‘‘‘ 2019 The Editor(s) (if applicable) and The Author(s) 2019 C

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https://doi.org/10.1007/978-1-4612-5282-5s in their patients to be caused by tuberculosis or leprosy, when they observed numerous acid-fast bacilli in the biopsy specimens [1]. The typical duration of illness was between 1 and 2 years; treatment was essentially surgical. With the advent of chemotherapy for tuberculosis [2–4], and later for
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https://doi.org/10.1007/BFb0070226ed on this success, WHO guidelines listed the application of heat as a treatment option for BU in 2000. However, the heat application devices initially employed were impractical. The phase change material (PCM) sodium acetate trihydrate, offers an ideal technical solution. Both, a proof-of-principle
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The maximum likelihood estimator, confirmed by several studies, including a randomised controlled clinical trial (Nienhuis et al., Lancet 375:664–672, 2010). Despite successful outcomes with this treatment regimen, the healing process is still characterized by long hospital stays as a result of delayed healing, in a significant pro
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Tiziano Squartini,Diego Garlaschellience rates between 1 and 5% in BU endemic countries. Evidence from Benin, Cameroon, Ghana and Gabon suggest that HIV may increase the risk of BU [1–5]. For example, in the . programme in Akonolinga, Cameroon, the prevalence of HIV was approximately 3–6 times higher in BU treated patients compared to
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https://doi.org/10.1007/978-3-030-11114-4Chronic Skin Infection; Host-Pathogen Interaction; Mycobacterial Infection; Neglected Tropical Diseases
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The Editor(s) (if applicable) and The Author(s) 2019
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