Titlebook: Buruli Ulcer; Mycobacterium Ulcera Gerd Pluschke,Katharina Röltgen Book‘‘‘‘‘‘‘‘ 2019 The Editor(s) (if applicable) and The Author(s) 2019 C

Intervention

Paul P. B. Eggermont,Vincent N. LaRiccia been reported from 34 countries, mainly with tropical and subtropical climates. Following a peak of 5954 reported BU cases globally in 2004 the number of new recorded cases has been decreasing over the past years. In 2016, a total of 1952 BU cases were reported to the World Health Organization (WHO

繁殖

Paul P. B. Eggermont,Vincent N. LaRicciath Côte d’Ivoire, Ghana, Benin, and Cameroon being the four most endemic countries. As the disease affects mainly populations in remote, rural areas, where access to formal healthcare structures is limited, the true prevalence of BU is difficult to gauge. The continued preference of BU patients in m

FRAX-tool

P. P. B. Eggermont,V. N. LaRicciars affecting residents of the Bairnsdale region in the temperate Australian state of Victoria. The disease was also recognised from the 1950s in tropical far north Queensland where it is called Daintree ulcer or Mossman ulcer. There are other small pockets of transmission in coastal Queensland and t

Bravura

P. P. B. Eggermont,V. N. LaRicciathe cases of BU in America with only a few cases reported in Suriname, Peru, Mexico and Bolivia in the past [2, 3]. Either BU is underdiagnosed and underreported in most of the continent; or the specific environmental conditions in French Guiana represent a unique niche for the disease to appear; or

SLING

P. P. B. Eggermont,V. N. LaRicciaue to Japan and potentially China. Genetic characterization of this species has begun, and the efficacy of various therapies has been analyzed. Although treatment with triple antimicrobial therapy comprising rifampicin (RFP; 450 mg/day), levofloxacin (LVFX; 500 mg/day), and clarithromycin (CAM; 800 

tic-douloureux

使绝缘

小平面

Luis J. Alías,Paolo Mastrolia,Marco Rigolirotic toxin that has shown the ability to interfere with the immune response. This poses an additional difficulty to the understanding of the immunological determinants for the outcome of infection, a fundamental step to develop better preventive or curative strategies. In this chapter, the immune r

暂时过来

Luis J. Alías,Paolo Mastrolia,Marco Rigoliy occur mainly at places where no or only sparse fur is present: the ears, paws and the nose. To date such naturally infected animals have only been detected in Australia. In order to tackle specific research questions in vivo, several experimental . infection animal models have been developed, of w

改变