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Titlebook: Bone Research Protocols; Miep H. Helfrich,Stuart H. Ralston Book 20031st edition Humana Press 2003

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https://doi.org/10.1007/978-3-642-58641-5es: bone-resorbing osteoclasts (OCs) which are uniquely capable of dissolving and removing a small volume of bone, and bone-forming osteoblasts that subsequently fill in these lacunae or pits with new bone tissue. Whereas osteoblasts originate from mesenchymal cell precursors, OCs derive from hemato
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Cryotherapy and Other Ablative Procedures, osteoclasts were thought to share a common progenitor cell with osteoblasts, bone-forming cells. Osteoclast formation occurring as a consequence of fusion of nonosteoblastic mononuclear precursor cells was suggested by a number of early investigators including Pommer (1883), Mallory (1912), La Cost
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Surgery for Breast Cancer Liver Metastases,bunit of the vitronectin receptor (VNR) and the calcitonin receptor (CTR). The extracellular degradative process, known as bone resorption, is the hallmark of the osteoclast, and includes removal of both the hydroxyapatite and organic components of the skeleton. For bone resorption to occur, osteocl
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Gastrointestinal Stromal Tumors,oped a mouse bone marrow culture system, in which osteoclasts are formed in response to several bone-resorbing factors such as 1α,25-dihydroxyvitamin D. [1α,25-(OH).D.], parathyroid hormone (PTH), prostaglandin E. (PGE.) and interleukin-11 (IL-11) (.,.). We also developed a mouse coculture system of
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Cornelis J. H. Velde,Paul H. Sugarbaker osteoclasts. In this assay, osteoblasts are stimulated with 1,25-dihydroxyvitamin D. (D3) to stimulate RANKL and macrophage colony-stimulating factor (M-CSF) expression. These factors then stimulate early osteoclast precursors present in the spleen or bone marrow cell populations to differentiate i
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Bruno F. Fernandes,Miguel N. Burnier Jrole in bone mineralization based on studies of chick bone fragments. Subsequently, Reynolds used bone explants to study collagen synthesis in bone (.) and to investigate the effects of a wide variety of other agents on bone turnover such as vitamin A (.), ascorbic acid (.), calcitonin (.,.), hydroco
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