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Titlebook: Bleomycin: Chemical, Biochemical, and Biological Aspects; Proceedings of a joi Sidney M. Hect Conference proceedings 1979 Springer-Verlag N

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Leistung in der Entwicklung des Kindes, mg exhibits a therapeutic effect on Hodgkin’s lymphoma. Recently, treatment by a combination of bleomycin and a . alkaloid or a platinum compound was found to have a therapeutic effect on testis tumors. Bleomycin treatment does not suppress immune function and does not damage bone marrow; however,
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https://doi.org/10.1007/978-3-658-19776-6lar products. Moreover, the retention time of a given compound on LC is sometimes useful for predicting what modification has occurred, (iv) The purity of BLM and its modification products can be verified by high-performance liquid chromatography (HPLC).
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,Vektorräume und lineare Abbildungen,n and in so doing apparently inactivate the drug. The addition of Pe(II)salts to the reaction mixture, on the other hand, under conditions which lead to.the formation of the Fe(II)-BLM complex, greatly enhances the DNA degradingability of bleomycin..
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https://doi.org/10.1007/978-3-658-18191-8 the principal cell target is DNA which is degraded by BLM both . and ... DNA cleavage is enhanced in the presence of reducing agents such as 2-mercaptoethanol, dithiothreitol, or ascorbate and by the addition of Fe(II) and requires oxygen.. The DNA cleavage is inhibited by Cu, Zn, Co, Mg, and EDTA.
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,Vektorräume und lineare Abbildungen,the reaction. The use of linear DNA in conjunction with velocity sedimentation analyses requires the introduction of many single- or double-strand breaks into the DNA before an appreciable (and measurable) decrease in the sedimentation velocity occurs. The use of such a limited technology precludes
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