Titlebook: Bleomycin: Chemical, Biochemical, and Biological Aspects; Proceedings of a joi Sidney M. Hect Conference proceedings 1979 Springer-Verlag N

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Jan Glaubitz,Daniel Rademacher,Thomas SonarDuring chemical studies of bleomycin (BLM), many fragments and derivatives have been isolated and characterized. The NMR spectra of these compounds were taken and analyzed for structural information.

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Verfahren für einfache ZusammenhängeFirst, this chapter summarizes our experimental results on the lesions produced by the antitumor drug, bleomycin, on DNA in solution. These results are compared critically with those reported in the literature in an attempt to assess the state of current knowledge in this area.

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NMR Study of BleomycinDuring chemical studies of bleomycin (BLM), many fragments and derivatives have been isolated and characterized. The NMR spectra of these compounds were taken and analyzed for structural information.

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The Action of Bleomycin on DNAFirst, this chapter summarizes our experimental results on the lesions produced by the antitumor drug, bleomycin, on DNA in solution. These results are compared critically with those reported in the literature in an attempt to assess the state of current knowledge in this area.

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圣歌

Leistung in der Entwicklung des Kindes,h bleomycin treatment and even cases of complete cure have been reported. Among the tumors belonging to this group, the well-differentiated type responds to bleomycin treatment with a very high frequency. There are patients who have lived more than 10 years after several courses of treatment with bl

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Intrinsische und extrinsische Motivation,ect verification of the proposed structure (which has been revised during this meeting by Dr. Umezawa and his co-workers) and hopefully extending the repertoire of available synthetic techniques, bleomycins of modified structure should facilitate the study of the mechanism of action of the drug and

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Unternehmenspolitische Schlußfolgerungenrolysis, proton and .C-NMR, infrared spectra and p..′ values (1)(.). A revised structure (2) containing an open chain β-aminopropionamide group instead of the β-lactam ring has been proposed at this symposium by Dr. Takita. It should be pointed out that the new structure (2) was considered to be one

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,Ausgangspunkte und Reflexionsanlässe,ophisticated natural products containing unusual amino acids as their building blocks .; they also have interesting glycosidic moieties . and are efficient chelating agents. In addition, new members of this family have recently been isolated . . The production of various bleomycins . and phleomycins