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Titlebook: Bioinformatics of Genome Regulation and Structure II; Nikolay Kolchanov,Ralf Hofestaedt,Luciano Milanesi Book 2006 Springer-Verlag US 2006

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Comparative Genomics and Evolution of Bacterial Regulatory Systemseveral different levels: microevolution of orthologous regulatory sites, changes in regulon content, evolution of interacting regulatory systems, and co-evolution of transcription factors and their binding signals. Regulatory interactions appear to be very dynamic in some cases and surprisingly stab
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New LTR Retrotransposable Elements from Eukaryotic Genomesrotransposons from a wide range of organisms. One of them is a systematic search of genomic sequences generated from whole genome sequencing projects. Here, we performed a computer analysis of 14 genomes with the aim of extracting LTR retrotransposons using a software based on the hidden Markov mode
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A Genome-Wide Identification of Mitochondrial DNA Topoisomerase I in cycle checkpoint control (Pommier, 1998). It is likely that at least three different plant topoisomerases function within nucleus, in mitochondria, and in chloroplasts. This hypothesis was partially supported by biochemical experiments (Daniell et al., 1995; Balestrazzi et al., 2000). Moreover, the
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Change in CpG Context is a Leading Cause of Correlation between the Rates of Non-Synonymous and Synot unexplained genome-level phenomenon, which is in disagreement with the neutral theory of molecular evolution (Kimura, 1983). Comparison of 7732 orthologous genes of mouse and rat confirms the previously observed correlation between the rates of substitutions in non-synonymous and synonymous nucleo
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Universal Seven-Cluster Structure of Genome Fragment Distribution: Basic Symmetry in Triplet Frequenenced bacterial genomes available in GenBank in August 2004, we show that there are four ‘pure’ types of the seven-cluster structure observed. The type of cluster structure depends on GC content and reflects basic symmetry in triplet frequencies. Animated 3D-scatters of bacterial genomes seven-clust
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New Methods to Infer DNA Function from Sequence Information regions, and non-coding non-regulatory DNA exhibit different statistical patterns. We suggest capturing and measuring these patterns by the following suite of statistical tools: (1) the ‘fluffy-tail’ test, a bootstrap procedure to recognize statistically significant abundant similar words in regula
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