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Titlebook: Bioinformatics of Genome Regulation and Structure II; Nikolay Kolchanov,Ralf Hofestaedt,Luciano Milanesi Book 2006 Springer-Verlag US 2006

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期刊全称Bioinformatics of Genome Regulation and Structure II
影响因子2023Nikolay Kolchanov,Ralf Hofestaedt,Luciano Milanesi
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发行地址Comprises the newest results obtained while researching into the structure and function of molecular genetic systems belonging to different complexity level of their organization.Covers the hottest it
图书封面Titlebook: Bioinformatics of Genome Regulation and Structure II;  Nikolay Kolchanov,Ralf Hofestaedt,Luciano Milanesi Book 2006 Springer-Verlag US 2006
影响因子The last 15 years in development of biology were marked with accumulation of unprecedentedly huge arrays of experimental data. The information was amassed with exclusively high rates due to the advent of highly efficient experimental technologies that provided for high throughput genomic sequencing; of functional genomics technologies allowing investigation of expression dynamics of large groups of genes using expression DNA chips; of proteomics methods giving the possibility to analyze protein compositions of cells, tissues, and organs, assess the dynamics of the cell proteome, and reconstruct the networks of protein-protein interactions; and of metabolomics, in particular, high resolution mass spectrometry study of cell metabolites, and distribution of metabolic fluxes in the cells with a concurrent investigation of the dynamics of thousands metabolites in an individual cell. Analysis, comprehension, and use of the tremendous volumes of experimental data reflecting the intricate processes underlying the functioning of molecular genetic systems are unfeasible in principle without the systems approach and involvement of the state-of-the-art information and computer technologies and
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Content Sensors Based on Codon Structure and DNA Methylation for Gene Finding in Vertebrate Genomesaneous deamination. This leaves different footprints on coding and non-coding sequences. We capture these different fingerprints by five indices that can be used to discriminate between coding and non-coding (intron) sequences. We also show that a linear discriminant function derived from a training
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Artsite Database: Comparison of , Selected and Natural Binding Sites of Eukaryotic Transcription Faceir DNA-binding domains obtained from . selected sequences. Current release of the database comprises 420 matrices describing specific features of binding sites or their DNA-binding domains for over 200 transcription factors. The matrices were constructed basing on alignments of representative sampl
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Analysis of Nucleosome Formation Potential and Conformational Properties of Human J1-J2 and D2-D1 Tynformational signals (codes) for compacting DNA of these regions into nucleosomes and chromatin structures of higher level. However, this aspect of informational content of alpha satellite primary DNA sequences yet requires further studies. Computer analysis of nucleosome formation potential (NFP) w
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