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Titlebook: Biochemistry of Arachidonic Acid Metabolism; William E. M. Lands Book 1985 Martinus Nijhoff Publishing, Boston 1985 Lipid.Nucleotide.bioch

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Prostanoid Receptors,nd Thrombanoic Acid, which form the basis of their nomenclature, Figure 1. PG and Tx can be termed collectively as Prostanoids because Tx are generated from PG endoperoxi des. Although mono-enoic (PG.,, Tx.) and tri-enoic (PG., Tx.) prostanoids may occur naturally, this paper will concentrate mainly
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Leukotrienes: Biological Properties, Evidence for Specific Receptor Sites and Evidence for the Invoy (1,2). The initial step in this pathway involves insertion of molecular O. at position C5 to produce 5-hydroperoxyeicosatetraenoic acid. This is followed by a dehydration step to produce an unstable epoxide intermediate (leukotriene A.). There are two enzymic routes of metabolism from leukotriene
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Ausgangslage und Fragestellung,r precursor of eicosanoids in mammalian tissues. These two acids appear to share a qualitatively similar overall reaction mechanism, but they have quantitatively different kinetic constants. There has been a tendency for researchers to use 18:2 when studying plant lipoxygenases and 20:4 with animal
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