Titlebook: Animal Models of Human Birth Defects; Aimin Liu Book 2020 Springer Nature Singapore Pte Ltd. 2020 Human birth defects.Animal model.Forward

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Book 2020rth defects and the essential role of animal models in shedding light on the underlying mechanisms of these disorders. Birth defects are the leading cause of infant deaths, and cost billions of dollars in care for those affected. Unfortunately, the lack of a clear understanding of the mechanisms lea

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https://doi.org/10.1007/978-90-481-3138-9ions can be modeled using human pluripotent stem cells. At the core of understanding of these molecular processes are animal model studies that continue to be essential for elucidating the mechanisms underlying human pancreatic functions and diseases.

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Animal Models of Pancreas Development, Developmental Disorders, and Disease,ions can be modeled using human pluripotent stem cells. At the core of understanding of these molecular processes are animal model studies that continue to be essential for elucidating the mechanisms underlying human pancreatic functions and diseases.

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What Do Animal Models Teach Us About Congenital Craniofacial Defects?,l bone, facial jaw bones, and two classes of diseases, ciliopathies and RASopathies. Studying the animal models of these rare diseases sheds light not only on the etiology and pathology of each disease, but also provides meaningful insights towards the mechanisms which regulate normal development of the head and face.

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Surya K. Mohanty,Debabrata Pandaas an excellent resource to identify the genetic bases of human kidney defects and have led to significantly improved diagnostics. Furthermore, genetic data from human CAKUT studies have also revealed novel genes regulating kidney differentiation.

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