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Titlebook: Allergy and Allergic Diseases; The New Mechanisms a Judah A. Denburg Book 1998 Springer Science+Business Media New York 1998 Immunity.infla

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期刊全称Allergy and Allergic Diseases
期刊简称The New Mechanisms a
影响因子2023Judah A. Denburg
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图书封面Titlebook: Allergy and Allergic Diseases; The New Mechanisms a Judah A. Denburg Book 1998 Springer Science+Business Media New York 1998 Immunity.infla
影响因子Allergy and Allergic Diseases has been organized to provide an up-to-date, clinically relevant compilation of one of the most exciting areas of investigation in medicine today-allergic disease, especially as it pertains to the skin, airways, and bowel. With the dramatic rise in the incidence of various allergic disorders worldwide, and the coming of age of the discipline of Clinical Immunology and Allergy, the interface between basic and clinical science in this arena demands highlighting in this comprehensive new syn­ thesis.1t is with the hope of filling this evident need that Allergy and Allergic Diseases: The New Mechanisms and Therapeutics has been put together. The book‘s content is divided into both basic and clinical sections, with emphasis on various components of the immune and inflammatory response as they relate to the development of allergic disease. Topics span the range from molecular biology to clinical symptomatology, with an effort to make this of interest to as broad a constituency as possible. This book will therefore be of substantial interest to specialists in Clinical Immunology and Allergy, scientists studying the cellular and molecular biology of in­ flamma
Pindex Book 1998
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Molecular Mechanisms of Isotype Switching to IgEwitch to a particular isotype, a B-cell needs to receive two signals: signal 1 is cytokine-dependent, results in the activation of transcription at a specific region of the Ig locus, and determines isotype specificity. Signal 2 activates the recombination machinery, and leads to DNA switch recombination.
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