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Titlebook: Allergy and Allergic Diseases; The New Mechanisms a Judah A. Denburg Book 1998 Springer Science+Business Media New York 1998 Immunity.infla

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Role of CD8+ T-Cells in the Regulation of Immunoglobulin Erin and degradative enzymes such as granzyme B. CD8. T-cells can kill MHC class-I peptide-bearing target cells via the Fas-dependent “kiss-of-death” pathway. In this chapter we will review the role of CD8. T-cells in IgE regulation.
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Cytokines and IgE Regulationntly exported to the plasma membrane, where they are recognized by T-cell receptor (TCR) .. In addition, activated B-cells express CD80 (B7-1) and CD86 (B7-2, B70), which are the counter receptors for CD28 and which provide a costimulatory signal for T-cell activation resulting in T-cell proliferati
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The Role of Mast Cells in Inflammation and Homeostasistions by releasing their mediators (e.g., biogenic amines, arachidonic acid metabolites, proteoglycans, proteinases, cytokines, etc.) in controlled amounts. These same mediators, however, released in large amounts under conditions of inflammation, can deleteriously affect other cells and tissues. To
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Human Langerhans Cellsn animal models, e.g., in the murine system, one should be aware that there are some important discrepancies between the human and murine LC and SIS. These will be mentioned appropriately whenever necessary.)
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