Titlebook: Allergy and Allergic Diseases; The New Mechanisms a Judah A. Denburg Book 1998 Springer Science+Business Media New York 1998 Immunity.infla

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Design and Use of Assistive Technologyribute to the induction of tissue damage. The mechanisms accounting for the joint involvement of IgE-producing B-cells, mast cells/basophils, and eosinophils in the pathogenesis of allergic reactions had remained unclear until the existence of two polarized forms of the cluster differentiation (CD)4

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Design and Use of Assistive Technologybservation has important implications for future therapeutic procedures since it suggests that drugs modulating T-lymphocyte function may be of considerable interest in allergic conditions and asthma. This chapter summarizes the possible role of T-cells in allergic diseases and possible therapeutic

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Cytokines and IgE Regulationesenting cells (APC). B-cell activation is initiated when specific B-cells recognize the allergen by cell surface immunoglobulin (sIg). However, costimulatory molecules expressed by activated T cells in both soluble and membrane-bound forms are necessary for differentiation of B-cells into Ig-secret

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