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Titlebook: Advances in Research on Neurodegeneration; Volume 7 Y. Mizuno,D. B. Calne,M. B. H. Youdim Conference proceedings 2000 Springer-Verlag Wien

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https://doi.org/10.1007/978-0-387-74778-1 some members are implicated in cancer and nuronal diseases..Here, I overview the mechanism of how Bcl-2 family proteins regulate cell death, and how they are implicated in human diseases, particularly focusing on role of Bcl-2 in spinal muscular atropy.
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SpringerBriefs in Computer Sciencethat the aggregate formation and apoptosis are partially suppressed by trans glutaminase inhibitors, raising the possibility that trans glutaminase is involved in the aggregate body. The results may open new prospects for developing therapeutic measures for the polyglutamine diseases.
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Structure Prediction of Membrane Proteins,ne therapy of PD is the protection of dopaminergic neurons in the substantia nigra using an AAV vector containing a glial cell line-derived neurotrophic factor (GDNF) gene. Combination of dopamine-supplement gene therapy and GDNF gene therapy would be a logical approach to the treatment of PD.
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Structure Prediction of Membrane Proteins, immune surveillance against HTLV-I and found that significant cytotoxic T lymphocyte activity, and suppressed natural killer activity and antibody-dependent cell-mediated cytotoxicity in the patients. These altered immune surveillance may be associated with the spread of HTLV-I infection and the pathogenesis of HAM/TSP.
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Role of anti-apoptotic Bcl-2 protein in spinal muscular atrophy, some members are implicated in cancer and nuronal diseases..Here, I overview the mechanism of how Bcl-2 family proteins regulate cell death, and how they are implicated in human diseases, particularly focusing on role of Bcl-2 in spinal muscular atropy.
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Dentatorubral-pallidoluysian atrophy (DRPLA),that the aggregate formation and apoptosis are partially suppressed by trans glutaminase inhibitors, raising the possibility that trans glutaminase is involved in the aggregate body. The results may open new prospects for developing therapeutic measures for the polyglutamine diseases.
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,Gene therapy of Parkinson’s disease using Adeno-Associated Virus (AAV) vectors,ne therapy of PD is the protection of dopaminergic neurons in the substantia nigra using an AAV vector containing a glial cell line-derived neurotrophic factor (GDNF) gene. Combination of dopamine-supplement gene therapy and GDNF gene therapy would be a logical approach to the treatment of PD.
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