Overview: The articles in Issue 4 of .Journal of Inherited MetabolicDisease., Vol. 14 (1991) contain the main lectures presented at the28th Annual Symposium of the Society for the Study of Inborn Errors ofMetabolism, Birmingham, UK, 1990, which was dedicated to `The Liverand Inherited Metabolic Disease‘ with a half-day workshop on`Screening and Economics‘. .The subjects covered include metabolic functions of the liver, bileacids, alpha-1-antitrypsin deficiency, tyrosinaemia type I,Crigler-Najjar disease type I and Niemann-Pick disease type C,providing updates on a wide range of metabolic disor
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