Overview: Peroxisomal disorders constitute a major research front inclinical genetics, paediatrics and cell biology. Since 1983, themetabolic defect in some 20 different peroxisomal disorders has beendescribed. The best known conditions include Zellweger syndrome,rhizomelic chondrodysplasia punctata and X-linked adrenoleukodystrophyand, in the most recent edition of .The Metabolic and MolecularBasis Inherited. .Disease., edited by Scriver and colleagues,more than 100 pages are now devoted to the subject. .Progress in our understanding of these conditions, and theirdiagnosis, results from the a
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