Titlebook: Vitamin D; Physiology, Molecula Michael F. Holick Book 19991st edition Humana Press 1999 Absorption.Calcium.Metabolite.Public Health.Vitami

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Nongenomic Rapid Effects of Vitamin D,ntiation is largely unknown. Specific nuclear vitamin D receptors (nVDRs) for this secosteroid have been found in numerous organs and cell lines .. The binding of 1α,25(OH).D. to the nVDR and subsequent binding of the hormone-receptor complex to selected DNA sequences were thought to be the mechanis

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Vitamin D and Bone Health in Adults and the Elderly, absorption in the intestine, vitamin D is essential for normal mineralization of bone and has major regulatory effects on bone cells in the bone remodeling unit. In addition to distant skeletal and intestinal effects, the active form of vitamin D, 1,25-dihydroxyvitamin D. [1,25(OH).D.], also regula

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Inherited Defects of Vitamin D Metabolism, to the biologic effects of the active metabolite), presents primarily with signs and symptoms that reflect impaired intestinal calcium absorption. These include signs and symptoms of neuromuscular irritability, including tetany and seizures, which are a direct result of the hypocalcemia. Long-stand