| 书目名称 | Validation of Alternative Methods for Toxicity Testing |
| 编辑 | Chantra Eskes,Maurice Whelan |
| 视频video | |
| 概述 | Practical insights from experts on current best practice in a fast-evolving field.Insights on current challenges for the validation of novel technologies.An overview of innovative approaches to method |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | .This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. . .Validation of Alternative Methods for Toxicity Testing .is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal an |
| 出版日期 | Book 2016 |
| 关键词 | Computational methods; Human-on-a-chip; In Vitro; Toxicity Testing; Transcriptomics; Validation |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-33826-2 |
| isbn_softcover | 978-3-319-81612-8 |
| isbn_ebook | 978-3-319-33826-2Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 17:36:00
