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Titlebook: United States-Japan Seminar on Host-Guest Chemistry; Proceedings of the U George W. Gokel,Kenji Koga Conference proceedings 1989 Kluwer Aca

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Cyclophanes as Hosts for Aromatic and Aliphatic GuestsA series of water-soluble cyclophanes, made by connecting two diarylmethane units and two bridging chains via four nitrogens, were found to provide hydrophobic cavities of definite shape and size for forming inclusion complexes with various organic compounds in aqueous solution. Some chemical modifications of these cyclophanes are described.
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James J. Christensen 1931–1987This issue of the Journal is dedicated to the memory of the late Professor James J. Christensen. Professor Christensen died suddenly at his home on September 5, 1987. He was 56 years old.
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The Preparation of Ribose-Free ‘Artificial Dinucleotides’: A New Approach to Molecular Recognition?ribose-free system to be prepared and characterized in which molecular recognition by complementary guanine-cytosine base-pairing might be possible. It is thus prototypical of a new and potentially large class of ‘artificial oligonucleotides’.
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Artificial Hydrolase Using Modified Dimethyl-,-cyclodextrinnd the enzymatic activities of . were investigated. . caused an 1100-fold increase in the rate of hydrolysis of .-nitrophenyl acetate at pH 7.2, whereas unmodified ß-DMCD depressed the reaction. The kinetic p.. of . was 7.2, and the .. of . was independent of pH values. . had .-selectivity for the hydrolysis of nitrophenyl acetate isomers.
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