Titlebook: Understanding Aging, Fatigue, and Inflammation; When the Immune Syst Rainer H. Straub Book 2024 The Editor(s) (if applicable) and The Autho

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Loss of Appetite, Malnutrition, and Undernutrition an acute stressful life situation must be managed. Since foraging is energetically expensive, it is reduced to make the energy released available to the immune system or the brain/muscles. Then problems such as malnutrition and undernutrition, but also loss of muscle mass (protein loss) with simult

AMOR

Muscle Loss day 2–3 onwards, fat is primarily used. It is therefore a positively selected program for providing energy in a state of hunger. In chronic inflammations, this program is used again, and cytokines are significantly involved in muscle breakdown. Furthermore, endogenous androgen loss and immobility p

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Weight Changes (Increase and Decrease)mpared to great apes, this is, for example, the better energy storage in adipose tissue. In addition, energy shortages in the womb are crucial for a non-genetically determined weight gain in childhood (Barker phenomenon). In chronic inflammation, patients tend to have a normal weight or at most slig

变异

The Storage Hormone Insulin Doesn’t Work—Insulin Resistanceevent of acute inflammation or an acute fight or flight response, it is important to switch off the effect of insulin (inducing insulin resistance) so that the now increasingly circulating glucose molecules and fatty acid molecules are supplied to the immune system or the brain/muscles. This evoluti

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腼腆

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The Storage Hormone Insulin Doesn’t Work—Insulin Resistancedipose tissue. Age-related diabetes is the result of this long-term unfavorable development with increasing destruction of insulin production in the pancreas. Nevertheless, insulin resistance is an evolutionarily positively selected mechanism that serves an overactive selfish brain or a highly active selfish immune system.

Anticoagulant

AMOR

Sleep Disorders and Circadian Symptoms the final result during aging is similar to chronic inflammation; it leads to higher unwanted energy expenditure. These unwanted energy expenditures prevent voluntary energy expenditures during the day through physical and mental activity.