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Titlebook: siRNA and miRNA Gene Silencing; From Bench to Bedsid Mouldy Sioud Book 2009 Humana Press 2009 Gene and immunotherapy.Gene regulation.In viv

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书目名称siRNA and miRNA Gene Silencing
副标题From Bench to Bedsid
编辑Mouldy Sioud
视频video
概述Unparalleled diversity of siRNA delivery and imaging strategies covered in a single volume.Details the strategies that predict the design of effective siRNA with minimum side effects.Fully explains mi
丛书名称Methods in Molecular Biology
图书封面Titlebook: siRNA and miRNA Gene Silencing; From Bench to Bedsid Mouldy Sioud Book 2009 Humana Press 2009 Gene and immunotherapy.Gene regulation.In viv
描述.RNA interference has become a key method in the suppression of gene expression and the development of therapeutic agents, yet there is still the problem of delivery, stability, and the danger of off-target effects such as the silencing of unwanted genes and activation of innate immunity. In .siRNA and miRNA Gene Silencing: From Bench to Bedside., expert researchers explore the most recent advances in siRNA design, expression, delivery, .in vivo. imaging, and methods to minimize siRNA’s unwanted effects and promote successful use in patients. As part of the highly successful .Methods in Molecular Biology™. series, the chapters focus on their respective subjects with easy-to-use, up-to-date information, including several step-by-step laboratory protocols on topics such as new delivery formulations and strategies with promising applications .in vitro .and .in vivo., validated therapeutic target genes, and components of miRNA function, biogenesis, and interference with virus infection...Comprehensive and cutting-edge, .siRNA and miRNA Gene Silencing: From Bench to Bedside. offers an excellent collection of chapters to aid all those with an interest in RNAi, gene regulation, and new th
出版日期Book 2009
关键词Gene and immunotherapy; Gene regulation; In vivo imaging; RNA interference; Regulation; Small interfering
版次1
doihttps://doi.org/10.1007/978-1-60327-547-7
isbn_softcover978-1-61737-908-6
isbn_ebook978-1-60327-547-7Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightHumana Press 2009
The information of publication is updating

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Local and Systemic Delivery of siRNAs for Oligonucleotides Therapy,the evaluation of siRNA potency in vivo is central for the selection of therapeutic siRNAs. In this chapter, the effects of atelocollagen-delivered siRNAs in live animals were monitored using bioluminescence imaging.
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Imaging of siRNA Delivery and Silencing,cation for siRNA imaging. It is noteworthy that new publications in this field appear almost on a weekly basis and the authors have made a sincere attempt to reflect the development of this area in their review.
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