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Titlebook: Systems Biology; Nikolaus Rajewsky,Stefan Jurga,Jan Barciszewski Book 2018 Springer International Publishing AG, part of Springer Nature 2

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发表于 2025-3-21 18:07:46 | 显示全部楼层 |阅读模式
书目名称Systems Biology
编辑Nikolaus Rajewsky,Stefan Jurga,Jan Barciszewski
视频video
概述Presents a wide spectrum of topics from fundamentals of modelling networks, to image-driven systems biology and personalized medicine.Combines fundamentals with clinical and agricultural applications.
丛书名称RNA Technologies
图书封面Titlebook: Systems Biology;  Nikolaus Rajewsky,Stefan Jurga,Jan Barciszewski Book 2018 Springer International Publishing AG, part of Springer Nature 2
描述Many breakthroughs in experimental devices, advanced software, as well as analytical methods for systems biology development have helped shape the way we study DNA, RNA and proteins, on the genomic, transcriptional, translational and posttranslational level. This book highlights the comprehensive topics that encompass systems biology with enormous progress in the development of genome sequencing, proteomic and metabolomic methods in designing and understanding biological systems..Topics covered in this book include fundamentals of modelling networks, circuits and pathways, spatial and multi cellular systems, image-driven systems biology, evolution, noise and decision-making in single cells, systems biology of disease and immunology, and personalized medicine. Special attention is paid to epigenomics, in particular environmental conditions that impact genetic background. The breadth of exciting new data towards discovering fundamental principles and direct applicationof epigenetics in agriculture is also described..The chapter “Deciphering the Universe of RNA Structures and Trans RNA-RNA Interactions of Transcriptomes in vivo - from Experimental Protocols to Computational Analyses”
出版日期Book 2018
关键词regulatory networks; computational methods; genome sequencing; proteomics; metabolomics; image-driven sys
版次1
doihttps://doi.org/10.1007/978-3-319-92967-5
isbn_softcover978-3-030-06559-1
isbn_ebook978-3-319-92967-5Series ISSN 2197-9731 Series E-ISSN 2197-9758
issn_series 2197-9731
copyrightSpringer International Publishing AG, part of Springer Nature 2018
The information of publication is updating

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发表于 2025-3-22 00:04:10 | 显示全部楼层
,Deciphering the Universe of RNA Structures and , RNA–RNA Interactions of Transcriptomes In Vivo: Frteractions. The overall performance of these methods thus strongly depends on the experimental and the computational protocols employed. In order to get the best out of both worlds, both aspects need to be optimised simultaneously. This review introduced the methods and proposes ideas how they could be further improved.
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发表于 2025-3-22 07:46:42 | 显示全部楼层
Robust Approaches to Generating Reliable Predictive Models in Systems Biology,ffective, fast, and suggests it can be used as an initial filtering step in conjunction with other computational techniques. Finally, other potential methods to construct a set of reliable network models using time-course data are explored.
发表于 2025-3-22 11:08:45 | 显示全部楼层
Nanocellulose: A New Multifunctional Tool for RNA Systems Biology Research,hese interactions, nanocellulose provides a strong scaffolding platform; we evaluate different application modes regarding such uses of nanocellulose. Nanocellulose also provides options with which to probe biomedical RNA interactions. Future perspectives of nanocellulose use in various fields are discussed.
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发表于 2025-3-22 17:28:57 | 显示全部楼层
Hints from Information Theory for Analyzing Dynamic and High-Dimensional Biological Data,ctive local processes but also on the subtle, yet robust, global-scale behavior. Furthermore, these techniques are swift in utility, as no detailed a priori knowledge of the biological system in study is required, and avoid “biased” expression cutoffs that are usually required for traditional/reductionist approaches.
发表于 2025-3-22 21:44:00 | 显示全部楼层
,Systems Approaches to Map In Vivo RNA–Protein Interactions in ,,nct proteins. Here, we discuss recent progress to obtain a systems-level understanding of in vivo RNA–protein interactions in the reference plant . using protein-centric and RNA-centric methods as well as combined protein binding site and structure probing.
发表于 2025-3-23 05:04:13 | 显示全部楼层
Is Autogenous Posttranscriptional Gene Regulation Common?,ted effort to understand the regulation of specific genes. The paucity of examples from higher eukaryotes may be due to the difficulty of identifying them using common approaches for uncovering regulatory interactions. An alternative approach is proposed that can fill the gap.
发表于 2025-3-23 09:10:50 | 显示全部楼层
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