Titlebook: Systemic Sclerosis; Kazuhiko Takehara,Manabu Fujimoto,Masataka Kuwana Book 2016 Springer Japan 2016 Autoimmune disease.Cytokine.Fibrosis.I

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adjacent

Ayumi Yoshizaki,Shinichi Satodesign engineers involved in product design, analysis, and validation. It equips them with an understanding of the theoryand essentials and also with practical skills needed to apply this understanding in real world design and manufacturing settings. .978-3-030-09031-9978-3-319-74594-7

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Toshiyuki Yamamotodesign engineers involved in product design, analysis, and validation. It equips them with an understanding of the theoryand essentials and also with practical skills needed to apply this understanding in real world design and manufacturing settings. .978-3-030-09031-9978-3-319-74594-7

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健谈

Minoru Hasegawaficiently. It is a valuable tool for designers, as well as for advanced undergraduate and postgraduate students. The exercises it contains allow readers to try out different aspects of the subject matter and the book also includes projects that can be used for teaching purposes..978-1-4471-6902-4978-0-85729-259-9

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Fibrosis: Overview,ix synthesis. TGF-β is known to induce the expression of extracellular matrix proteins in mesenchymal cells and to stimulate the production of protease inhibitors that prevent enzymatic breakdown of the extracellular matrix. This chapter focuses on the mechanism of fibrosis in SSc.

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Autoimmunity in Systemic Sclerosis: Overview,rly, SSc patients have B cell abnormalities characterized by chronic hyper-reactivity of memory B cells, possibly due to CD19 overexpression. CD19 is a crucial regulator of B cell activation. Recent studies demonstrated B cells from SSc patients show an upregulated CD19 signaling pathway that induce