书目名称 | Synthesis of Functionalized Organoboron Compounds Through Copper(I) Catalysis |
编辑 | Koji Kubota |
视频video | |
概述 | Nominated by Hokkaido University as an outstanding Ph.D. thesis.Focuses on the state-of-the-art of copper(I)-catalyzed borylation reaction.Provides details both of the reaction development and of theo |
丛书名称 | Springer Theses |
图书封面 |  |
描述 | This book describes state-of-the-art borylation chemistry using copper(I) catalysis. Enantioselective reactions are included to afford a variety of functionalized, complex organoboronate esters, which will find wide application in asymmetric synthesis, drug discovery, and material science. Organoboron compounds are recognized as useful reagents in organic synthesis; therefore, great effort has been devoted to the development of a simple, mild, and efficient method for their preparation in the past several years. However, the synthesis of functionalized organoboron compounds remains a challenging issue because known reactions often require the use of highly reactive organometallic carbon nucleophiles. This book focuses on conceptually new, formal nucleophilic copper(I)-catalyzed borylation reactions with diboron compounds that show high selectivity and excellent functional group compatibility. Theoretical studies based on density functional theory calculations to understand the reactionmechanisms have also been described. Advances in this novel borylation chemistry will allow the rapid and efficient synthesis of complex molecules with potentially interesting properties in combinatio |
出版日期 | Book 2017 |
关键词 | Organoboron compound; Enantioselective borylation; Nucleophilic borylation; Copper catalyst; Diboron com |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-10-4935-4 |
isbn_softcover | 978-981-13-5271-3 |
isbn_ebook | 978-981-10-4935-4Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
issn_series | 2190-5053 |
copyright | Springer Nature Singapore Pte Ltd. 2017 |