Titlebook: Sugar Chains; Decoding the Functio Tadashi Suzuki,Kazuaki Ohtsubo,Naoyuki Taniguchi Book 2015 Springer Japan 2015 Cancer.Ganglioside.Glycom

Substitution

Mammalian Sialidase and Tumor Development,d glycolipids. They are found widely distributed in common in metazoan animals, from echinoderms to mammals, and also in viruses and other microorganisms. In mammals, there are four types of sialidase (NEU1, NEU2, NEU3, and NEU4), encoded by different genes differing in their major subcellular local

拾落穗

Roles of Glycans in Immune Evasion from NK Immunity,e natural killer (NK) cells. NK cells kill target cancer cells by two different rejection mechanisms, NK receptor-dependent killing and tumor-necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated killing. In spite of these tumor rejection systems, cancer cells make survival in host, fac

Limited

Glycomic Analysis of Cancer,hemical studies have suggested the involvement of aberrant glycosylation in cancer malignancy, such as metastasis and invasion. Furthermore, altered carbohydrate determinants, including tumor-associated carbohydrate antigens such as SLe. (CA19-9), have been utilized as useful tumor markers for the d

面包屑

Glyco-Predisposing Factor of Diabetes, pancreatic β-cells. The disappearance of GLUT2 from the β-cell surface is one of the early markers of the onset of type 2 diabetes, though the molecular mechanism has not been well understood. Recent advance in glycophysiology revealed that specific GLUT2 glycosylation by GnT-IVa is required for th

mediocrity

心胸狭窄

,-Mannosyl Glycan and Muscular Dystrophy,ns and .-glycans, according to their glycan-peptide linkage regions. The development of sensitive methods for analyses of glycan structures has identified .-mannosyl glycans in mammals; these structures used to be considered specific to yeast. Originally, .-mannosyl glycan was considered to be prese

ornithology

Glycans and Chronic Obstructive Pulmonary Disease (COPD),environmental exposures and host susceptibility factors should be taken into account in its management. Although cigarette smoke is the major risk factor, quitting smoking does not fully repress the airway inflammation and restore the lost lung function..Our group has been interested in changes of g

补角

,α1,6-Fucosyltransferase Knockout Mice and Schizophrenia-Like Phenotype,ge on N-linked glycans (N-glycans) in mammals. N-glycan is always attached to the nitrogen atom of an asparagine (Asn) side chain that is present in the Asn-X-Ser/Thr motif on a protein, where X is any amino acid except proline. The α1,6-fucosylated (core-fucosylated) N-glycan is ubiquitously distri

outer-ear

Glycan Structure and Neural Plasticity,tory glycans and focuses primarily on structural divergence among sulfated GAG chains and their unique and/or partially overlapping contributions to neuronal plasticity during development and during regeneration after central nervous system injury.

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