Titlebook: Sugar Chains; Decoding the Functio Tadashi Suzuki,Kazuaki Ohtsubo,Naoyuki Taniguchi Book 2015 Springer Japan 2015 Cancer.Ganglioside.Glycom

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书目名称Sugar Chains影响因子(影响力)




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弹药

,-Glycans and Quality Control of Proteins,glycans to carrier proteins resulting in changes in their physicochemical properties, such as solubility or heat stability, as well as physiological properties, such as bioactivity or intra- or intercellular trafficking. In addition, recent studies have revealed that .-glycans can act as a readout f

gnarled

Glycan-Mediated Protein Transport from the Endoplasmic Reticulum,insic sorting signals that are recognized by transport machineries. Efficient sorting of several secretory proteins requires cargo receptors that recognize the sorting signals of specific proteins and sort them into transport vesicles. In the early secretory pathway from the endoplasmic reticulum (E

Aromatic

Gangliosides and T-Cell Immunity, acid residues linked to the galactose residue in the second position from the ceramide backbone. Gangliosides are fundamental constituents of lipid rafts in eukaryotic cell membranes and are considered to play a variety of roles in cell physiology such as modulation of signal transduction. As with

Archipelago

Gangliosides Regulate Tumor Properties: With Focus on the Suppression of Metastasis-Associated ppGaliosides are expressed in a tumor-specific manner in neuroectoderm-derived cancers and T-cell leukemias. They are also expressed in small cell lung cancers and osteosarcomas. Not only as tumor markers but as functional molecules on the cell surface membrane, they have been of interest, and indeed th

enchant

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Discovery and Applications of a Novel Human Pluripotent Stem Cell-Specific Lectin Probe rBC2LCN,s exhaustively analyzed using the cutting-edge glycan profiling technology called high-density lectin microarray. Despite the different glycan profiles of the original somatic cells for each tissue, it was found that hiPSCs derived from various origins showed almost the same profile, indicating that

Intend

卵石

The Involvement of Midkine, a Heparin-Binding Growth Factor, in Cancer Development,dkine consists of two domains, an N-terminal and a C-terminal domain. Previous reports have emphasized the significance of the C-terminal domain, which contains clusters of basic amino acids (clusters I and II). Cluster I is mainly responsible for the strong affinity of midkine to heparin. In additi

敬礼

Tumor-Associated Glycans and Their Functional Roles in the Multistep Process of Human Cancer Progreal glycans on the surface of cancer cells. A variety of glycans are expressed in nonmalignant epithelial cells, including several normal glycans serving as ligands for siglecs, the immunosuppressive molecules carried by interstitial immune cells. These normal glycans decrease or disappear and are re