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Titlebook: Sucralfate; From Basic Science t Daniel Hollander,Guido N. J. Tytgat Book 1995 Springer Science+Business Media New York 1995 chemistry.clin

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Effect of Sucralfate on Experimental Ulcers been described in the preceding chapters. In this chapter, a detailed account will be given of the results of experimental studies of sucralfate conducted to assess its effects in preventing and heal- ing a variety of experimental ulcers induced in animals, and also of their correlation with the results of clinical use of the drug in humans.
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Vascular Factorstion in the stomach and duodenum. If ischemia was considered, it was ascribed to external or internal (e.g., thrombosis) narrowing and not to active involvement of endothelial cells (e.g., in regulating vascular permeability).
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Binding of Sucralfate to the Mucosal Surfaces on gastric acid secretion has its own fascination. As will become apparent, even the initial event following administration of this agent-the binding of sucralfate to the mucosa of the upper gastrointestinal tract-is not as straightforward as it might seem.
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Book 1995e history ofsucralfate‘s development, mechanisms of action, clinical efficacy,and future directions for research. This volume will be of interestto scientists and clinicians working in gastroenterology andgastrointestinal physiology.
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