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Titlebook: Subcellular Basis of Contractile Failure; Proceedings of the S Borivoj Korecky,Naranjan S. Dhalla Conference proceedings 1990 Kluwer Academ

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Role of Free Radicals in the Development of Ischemic Heart Disease and infarction (1–6). Up to 6 years ago it was generally believed that the degree of ischemic damage following a coronary occlusion was simply determined by the ratio of oxygen supply to the oxygen demand of the heart. Consequently, therapeutic interventions have been employed to reduce the demand
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Involvement of Sodium-Calcium Exchange in Cardiac Pathologylular ion transport pathways, and ii)biochemical studies using isolated sarcolemmal membranes. In addition, the mechanisms which may be responsible for the change in sodium-calcium exchange will be discussed.
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