Titlebook: Squamous Cell Head and Neck Cancer; Recent Clinical Prog David J. Adelstein Book 2005 Humana Press 2005 brachytherapy.cancer.carcinoma.cell

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The Role of Tumor Hypoxia in Head and Neck Cancer Radiotherapy,eering work of Gray and colleagues (.) demonstrating an oxygen dependency in the radiosensitivity of cells and tissues. During this period, interest among researchers has waxed and waned as promising new directions emerged from the laboratory, only to fail in clinical trials. However, with the emerg

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Induction Chemotherapy in Head and Neck Cancer,ponse rates of 20 to 50% in patients with previously untreated locally advanced head and neck cancer (.,.). The use of chemotherapy prior to radiation or surgery is commonly referred to as induction or neoadjuvant chemotherapy. Investigators hypothesized that the addition of an active induction regi

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Concurrent Chemoradiotherapy,t schedules. Given the impressive response rates seen with multiagent chemotherapy in previously untreated patients, considerable effort went into the study of induction or neoadjuvant treatment schedules (.). Numerous randomized trials have now been completed. Although induction chemotherapy has be

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Strategies for Protecting Normal Tissue in the Treatment of Head and Neck Cancer, cell carcinoma of the head and neck (HNSCC). The concept of the therapeutic ratio (TR) is fundamental to the understanding of this issue. The TR can be qualitatively defined as the TCP/NTCP where TCP is the tumor control probability and NTCP is the normal tissue complication probability. Both of th

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Chemoprevention in Head and Neck Cancer,000 new cases diagnosed yearly in the United States (estimated to be 56,520 cases in 2004 [.]) and 600,000 worldwide according to the latest numbers from the International Agency for Research on Cancer, World Health Organization. HNSCC accounts for 2% of all cancer deaths in the United States (.) an