Titlebook: Sphingolipids and Metabolic Disease; L. Ashley Cowart Book 2011 The Editor(s) (if applicable) and The Author(s), under exclusive license t

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Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/s/image/874250.jpg

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Heart Sphingolipids in Health and Disease, and sphingosine-1-phosphate in the development and prevention of ischemia/reperfusion injury of the heart. In the last section of this chapter we discuss the evidence for a role of ceramide in myocardial lipotoxicity.

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0065-2598 s findings that sphingolipids may regulate cholesterol homeoCurrent thinking holds that obesity derives primarily from overnutrition (though compelling arguments for other mechanisms, like endocrine disruption by environmental pollutants, also gain support from the literature). In animals, overnutri

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Sphingolipids and Cardiovascular Diseases: Lipoprotein Metabolism, Atherosclerosis and Cardiomyopat accumulate within the arterial wall and perhaps are oxidized to more toxic lipids. Both lipid accumulation and vascular reaction to the lipids lead to the gradual thickening of the vascular wall. A second major process that in some circumstances is a primary event is the development of a local infl

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