Titlebook: Sphingolipids and Metabolic Disease; L. Ashley Cowart Book 2011 The Editor(s) (if applicable) and The Author(s), under exclusive license t

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Blood Sphingolipids in Homeostasis and Pathobiology,tiation, proliferation and apoptotic cell death. Sphingolipids in blood constitute part of the circulating lipoprotein particles (HDL, LDL and VLDL), carried by serum albumin and also present in blood cells and platelets. Recent lipidomic and proteomic studies of plasma lipoproteins have provided in

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Glycosphingolipids and Insulin Resistance,. In recent times a crucial role for glycosphingolipids in insulin resistance has been proposed. A chronic state of insulin resistance is a rapidly increasing disease condition in Western and developing countries. It is considered to be the major underlying cause of the metabolic syndrome, a combina

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Glycosphingolipids and Kidney Disease,e known to play an important role in organ function at least in part from inherited lipid storage diseases such as Anderson-Fabry disease (Fabry’s disease; FD) that results from a mutation in alpha-galactosidase a (α-GLA or α-Gal A), the enzyme responsible for catalyzing the removal of terminal gala

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Book 2011by environmental pollutants, also gain support from the literature). In animals, overnutrition is initially handled by adipose tissue expansion; however, exhaustion of this route of lipid sequestering results in oversupply of lipid to other tissues including skeletal muscle, heart, liver, and others

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and 1980s, and it eventually became one of the most praised paradigms in the history of violence and criminal justice. Over the past forty years, the theory of civilising process has been a major model for analysing the long-term decline of homicide in Western Europe as a result of the taming of ind

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