Titlebook: Sphingolipid Biology; Yoshio Hirabayashi,Yasuyuki Igarashi,Alfred H. Mer Book 2006 Springer-Verlag Tokyo 2006 Activation.Lipid.base.biolog

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Sphingosine-1-Phosphate Lyasechain bases generated through the actions of sphingosine kinase may be dephosphorylated by lipid phosphatases or cleaved at the C. carbon-carbon bond by the pyridoxal 5’-phosphate-dependent enzyme, sphingosine-1-phosphate lyase. By regulating intracellular levels of phosphorylated long chain bases,

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Book 2006hingolipid biosynthesis, transport and membrane organization/lipid rafts; genetic approaches to understanding the roles of membrane sphingolipid biosynthesis; sphingolipid metabolism, specific G protein-coupled receptors (GPCRs), and signal transduction; and sphingolipid-associated disease and drug development..

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Ceramide 1-Phosphateing: membrane fusion, inflammation, DNA-synthesis, intracellular Ca. increase, and other processes. These CERK/C1P functions and the investigations over of the past decade that revealed them are reviewed here.

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