Titlebook: Sperm Acrosome Biogenesis and Function During Fertilization; Mariano G. Buffone Book 2016 The Editor(s) (if applicable) and The Author(s),

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The Molecules of Sperm Exocytosis, Specialized secretory cells undergo regulated exocytosis in response to physiological signals. Sperm exocytosis or acrosome reaction (AR) is essentially a regulated secretion with special characteristics. We will focus here on some of these unique features, covering the topology, kinetics, and mole

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Role of Actin Cytoskeleton During Mammalian Sperm Acrosomal Exocytosis,ired during the course of sperm capacitation. This review is focused on one aspect related to this acquisition: the role of the actin cytoskeleton. Evidence from different laboratories indicates that actin polymerization occurs during capacitation, and the detection of several actin-related proteins

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Site of Mammalian Sperm Acrosome Reaction,act. Because AR is an essential process that enables the spermatozoon to fertilize, it is generally believed that it occurs at a specific step during sperm–egg interaction. It is generally thought that “the site of action coincides with the site of commitment.” Thus, understanding the roles of AR an

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The Molecules of Sperm Exocytosis,lly a regulated secretion with special characteristics. We will focus here on some of these unique features, covering the topology, kinetics, and molecular mechanisms that prepare, drive, and regulate membrane fusion during the AR. Last, we will compare acrosomal release with exocytosis in other model systems.

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