| 书目名称 | Sildenafil | | 编辑 | Udo Dunzendorfer | | 视频video | | | 概述 | Topical volume about a landmark discovery.Written by leading experts in the field.Detailed and up-to-date knowledge base.Includes supplementary material: | | 丛书名称 | Milestones in Drug Therapy | | 图书封面 |  | | 描述 | ..This drug is a landmark discovery, which consequently has become the definitive therapy for the treatment of erectile dysfunction (ED). Following the major breakthrough in the field of nitric oxide (NO)-physiology and pharmacology leading to sildenafil being marketed, the most current information is presented in this reference book, including ongoing research from several disparate groups about NO as endothelium-derived relaxing factor (EDRF) and also as a neurotransmitter for nerves innervating erectile tissue in mammals...The development of sildenafil as an oral phosphodiesterase-5 (PDE5) inhibitor drug for the treatment of ED resulted in one of the first products, which made its way successfully from basic NO research to routine clinical therapy...This volume addresses all fields of sildenafil application in both men and women. In a highly competitive research environment with a critical medical need for drug improvements the reader will learn more about clinical resistance to sildenafil treatment and the modalities to overcome the failure rates. ..The individual chapters cover clinical use, pharmacokinetics, pharmacodynamics, biochemistry, and cultural aspects. They are writt | | 出版日期 | Book 2004 | | 关键词 | biochemistry; cancer; chemistry; development; drug; endothelium; erectile dysfunction; kinetics; pharmacodyn | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-0348-7945-3 | | isbn_softcover | 978-3-0348-9631-3 | | isbn_ebook | 978-3-0348-7945-3Series ISSN 2296-6056 Series E-ISSN 2296-6064 | | issn_series | 2296-6056 | | copyright | Springer Basel AG 2004 |
The information of publication is updating
|
|
发表于 2025-3-21 19:59:46
