Titlebook: Sex Steroids and Bone; Reinhard Ziegler,Johannes Pfeilschifter,Matthias B Conference proceedings 1994 Springer-Verlag Berlin Heidelberg 19

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Progesterone and Its Role in Bone Remodelling,reports are available which modify and extend the concepts presented in that paper. In particular, more work has recently been published on growth factors and progesterone in bone metabolism, on changes in bone markers during the luteal phase or with progestin therapy, and in both animal and human m

olfction

The Effect of Sex Steroids on Calciotropic Hormones In Vivo,in rats (Silver et al. 1986; Naveh-Many and Silver 1988, 1990) and in vitro (Silver et al. 1985; Okazaki et al. 1988; Cote et al. 1987). The PTH gene’s expression is also regulated by calcium, where the major effect is that of a low calcium increasing PTH mRNA levels in vivo (Rodriguez et al. 1991;

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Sex Steroids and Prostaglandins in Bone Metabolism, development of osteoporosis in women. Androgen deficiency may be as important in osteoporotic men (Foresta et al. 1985). The main effects of estrogen and androgen withdrawal are an increase in bone resorption with a smaller increase in bone formation and a consequent decrease in bone mass (osteopen

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Histomorphometric Studies of Bone Changes in Ovariectomized Rats and Their Prevention by Estrogen Res osteopenic changes in OVX rats and the bone-protective effect of estrogen replacement, as determined by histomorphometric techniques. The skeletal effects of estrogen depletion and replacement in OVX rats are compared briefly to those in postmenopausal and oophorectomized women.

丛林

Biochemical Assessment of Bone Metabolism in Rodents,ects presented by the other contributors to this volume. A number of methods are discussed which have proven to be powerful research tools, mostly in our institution, and have led, for example, to the clinical development of several bisphosphonates. These should also be useful tools for establishing