Titlebook: Serotonin: Molecular Biology, Receptors and Functional Effects; John R. Fozard,Pramod R. Saxena Book 1991 Birkhäuser Verlag 1991 biology.d

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Molecular Mechanisms of Action Induced by 5-HT3 Receptors in a Neuronal Cell Line and by 5-HT2 Receplls) and in a glioma cell line with 5-HT. receptors. In both cell lines, serotonin induces a transient rise of cytosolic Ca. activity. Ca. channel blockers (Ni. and La.) suppress the Ca. response to serotonin in the neuronal cells but not in the glial cells. When internal Ca. stores are depleted and

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Characterization of 5HT3 Receptor Mediated Electrical Responses in Nodose Ganglion Neurones and Clonnt response mediated by the opening of 5-HT. receptor-linked cation selective ion channels. 5-HT-induced currents reversed in sign at a potential close to 0 mV and desensitized rapidly. The conductance of the 5-HT. receptor ion channel complex in NlE-115 cells ( ~ 0.3 pS) was estimated to be approxi

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