Titlebook: Sequential Experimentation in Clinical Trials; Design and Analysis Jay Bartroff,Tze Leung Lai,Mei-Chiung Shih Book 2013 Springer Science+Bu

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Time-Sequential Design of Clinical Trials with Failure-Time Endpoints,eta-Blocker Heart Attack Trial (BHAT) in 1981. In Sects. 6.2 and 6.3, we describe the design details, interim analyses, and final report of BHAT. As the primary endpoint of BHAT was survival following at least one heart attack, we give an overview of survival analysis in Sect. 6.1. However, because

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Time-Sequential Design of Clinical Trials with Failure-Time Endpoints,he primary endpoint of BHAT was survival following at least one heart attack, we give an overview of survival analysis in Sect. 6.1. However, because of the sequential nature of interim analyses, traditional survival analysis methodology reviewed in Sect. 6.1 has to be extended to the sequential setting.

Tailor

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Stephan Moebius dialogue between the original work and antecedent adaptations, this chapter argues that this dialogue is additionally informed by individual actors, thus demonstrating that the contemporary pairing of Frankenstein’s monster and the vampire can be traced back to the first visual representation of th

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Prostatism