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Titlebook: Scientific Issues in Quantitative Cancer Risk Assessment; Suresh H. Moolgavkar Book 1990 Springer Science+Business Media New York 1990 DNA

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发表于 2025-3-21 19:00:00 | 显示全部楼层 |阅读模式
书目名称Scientific Issues in Quantitative Cancer Risk Assessment
编辑Suresh H. Moolgavkar
视频video
图书封面Titlebook: Scientific Issues in Quantitative Cancer Risk Assessment;  Suresh H. Moolgavkar Book 1990 Springer Science+Business Media New York 1990 DNA
描述In 1974, the Societal Institute of the Mathematical Sciences (SIMS) initiated.a series of five-day Research Application Conferences (RAC‘s) at Alta, Utah, for the purpose of probing in depth societal fields in light of their receptivity to mathematical and statistical analysis. The first 10 conferences addressed ecosys­ tems, epidemiology, energy, environmental health, time series and ecological processes, energy and health, energy conversion and fluid mechanics, environ­ mental epidemiology: risk assessment, atomic bomb survivor data: utilization and analysis, and modem statistical methods in chronic disease epidemiology. These Proceedings are a result of the eleventh conference of Scientific Issues in Quantitative Cancer Risk Assessment, which was held in 1989 at Snowbird, Utah. For five days, 45 speakers and observers contributed their expertise in the relevant biology and statistics. The presentations were timely and the discussion was both enlightening and at times spirited. This volume hopefully presents a record that will be useful both now and in the future. Suresh H. Moolgavkar of the Fred Hutchinson Cancer Research Center (Seattle, WA) and the University of Washington (Se
出版日期Book 1990
关键词DNA; Mathematica; cancer; cancer research; carcinogenesis; cell; epidemiology; growth; mechanics; statistics
版次1
doihttps://doi.org/10.1007/978-1-4684-9218-7
isbn_softcover978-1-4684-9220-0
isbn_ebook978-1-4684-9218-7
copyrightSpringer Science+Business Media New York 1990
The information of publication is updating

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Two Mutation Model for Carcinogenesis: Relative Roles of Somatic Mutations and Cell Proliferation iposure and rate of exposure. The results indicate that fractionation of exposure increases the lifetime probability of tumor, and that the efficiency of fractionation can be explained by the relative effects of radon daughters on the mutation rates and the kinetics of growth of initiated cells.
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Book 1990tah, for the purpose of probing in depth societal fields in light of their receptivity to mathematical and statistical analysis. The first 10 conferences addressed ecosys­ tems, epidemiology, energy, environmental health, time series and ecological processes, energy and health, energy conversion and
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The Clonogenic Cells of the Rat Mammary and Thyroid Glands: Their Biology, Frequency of Initiation,oid glands. Experiments with these systems have led to the conclusions a) that cancers are derived from small subpopulations of clonogenic cells in both organs, and b) that initiation, the first step in carcinogenesis, is a common event at the cellular level. It is postulated that any intracellular
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The Somatic Mutational Component of Human Carcinogenesis,. Such genetic changes are often used, explicitly or implicitly, as the transition device between stages in quantitative multistage models designed to describe carcinogenesis. Recent developments in the genetics of cancer and in somatic mutagenesis greatly increase our understanding of these process
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