Titlebook: Role of Transcription Factors in Gastrointestinal Malignancies; Ganji Purnachandra Nagaraju,Pallaval Veera‘Bramhac Book 2017 Springer Natu

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A Potential Role of Hypoxia-Inducible Factor-1 (HIF-1) in Esophageal Cancer,er types. Considering all parameters, HIF-1 inhibitor could present a potential approach to cancer therapy. This chapter summarizes the potential roles of HIF-1. in cell cycle, proliferation, apoptosis, and metastasis and future perspectives in targeting esophageal cancer for developing novel antica

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Role of STAT3 in Gastric Cancer Initiation, Development, and Progression,rolling numerous physiological processes such as cell propagation, differentiation, apoptosis, and angiogenesis by controlling the expression of critical genes in the pathway. Abnormal activation of STAT3 plays a key role in inflammation and transformation in numerous cancers including gastric cance

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,Curcumin: Its Role in Regulation of HIF-1α in Gastric Cancer, by downregulating the levels of the oncogene c-Myc expression and thereby hindering the expression of the targeted gene. Curcumin also exhibits antitumor effects under hypoxic conditions by significantly decreasing levels of hypoxia-induced HIF-1α protein, in cancer cells. Furthermore, curcumin eli

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,NF-κB: Its Role in Colorectal Cancer,d promote CRC malignant potential. These NF-κB target genes include those vital to cell cycle regulation, cell proliferation, metastasis, and cell survival. Additionally, activation of NF-κB in both cancerous cells and inflammatory cells and subsequent induction of cytokines/chemokines within the tu

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several signaling pathways involved in tumor growth, making them ideal targets for gastrointestinal cancer therapy. In closing, the book provides comprehensive descriptions of the major challenges associated with gastrointestinal cancer therapy..978-981-13-3893-9978-981-10-6728-0

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Tapan K. Barik,Surya N. Swainie Kapitel über die (Kristall-)Arthropathien leiten zu den degenerativen Gelenk- und Wirbelsäulenerkrankungen über, die einen wesentlichen und zunehmenden Stellenwert in der radiologischen Diagnostik einnehmen. Schließlich folgen noch ausführliche Kapitel zu Erkrankungen der Weichteile einschließlich ihrer Tumoren. .978-3-540-27612-8

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