| 书目名称 | Role of Capsaicin in Oxidative Stress and Cancer | | 编辑 | Sanjay K. Srivastava | | 视频video | | | 概述 | Thoroughly reviews the preventive and therapeutic effects of capsaicin in melanoma, pancreatic cancer, colon cancer, breast cancer, lung cancer, multiple myeloma and others.Identifies molecular and ce | | 丛书名称 | Diet and Cancer | | 图书封面 |  | | 描述 | This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway. | | 出版日期 | Book 2013 | | 关键词 | Cancer; Capsaicin; Oxidative stress; Prevention; Therapy; Apoptosis; gene expression | | 版次 | 1 | | doi | https://doi.org/10.1007/978-94-007-6317-3 | | isbn_softcover | 978-94-017-8429-0 | | isbn_ebook | 978-94-007-6317-3 | | copyright | Springer Science+Business Media Dordrecht 2013 |
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发表于 2025-3-21 17:32:15
