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Titlebook: Research in Congenital Hypothyroidism; François Delange,Delbert A. Fisher,Daniel Glinoer Book 1989 Plenum Press, New York 1989 assessment.

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Samuel Refetoff,Myriam Charbonneau,David H. Sarne,Junta Takamatsu,Jean H. Dussault
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Action of Thyroid Hormones on Brain Developmention of cretinism are found in the publication of the Royal Commission of the King of Sardaigna in 1848.. Cretinism is described as “a person with abnormal corporal development and mental retardation. They are born in regions were many such cases are found and endemic goiter is prevalent”.
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Iodine Nutrition and Congenital Hypothyroidisms frequency justifies systematic screening, which is extremely efficient and has an elevated benefit-cost ratio (2–3). In such countries CH is due principally to congenital anomalies in the development of the thyroid (4); it is unpredictable and unpreventable.
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978-1-4684-7582-1Plenum Press, New York 1989
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