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Titlebook: Research in Computational Molecular Biology; 12th Annual Internat Martin Vingron,Limsoon Wong Conference proceedings 2008 Springer-Verlag B

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A Fast, Alignment-Free, Conservation-Based Method for Transcription Factor Binding Site Discovery,ctive of orientation. We use this definition to derive informative priors over DNA sequence positions, and incorporate these priors into a Gibbs sampling algorithm for motif discovery. Our approach is simple and fast. It does not require sequence alignments, nor the phylogenetic relationships betwee
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Systems Metabolic Engineering,ng and developing strains having improved performance. In this lecture, I will present the general strategies of systems metabolic engineering. Also, several examples of applying systems metabolic engineering for the production of amino acids, primary metabolite (succinic acid) and secondary metabol
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