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Titlebook: Research in Computational Molecular Biology; 12th Annual Internat Martin Vingron,Limsoon Wong Conference proceedings 2008 Springer-Verlag B

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Transcriptional Regulation and Cancer Genomics,logy at the University of North Carolina, and Director of its Specialized Program of Research Excellence in Breast Cancer. From 1996–2001, Prof Liu was the Division Director of Clinical Sciences (Intramural program) at the US National Cancer Institute. In 2001, he was appointed the executive directo
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A Bayesian Approach to Protein Inference Problem in Shotgun Proteomics, that incorporates the predicted peptide detectabilities as the prior probabilities of peptide identification. Our model removes some unrealistic assumptions used in previous approaches and provides a rigorious probabilistic solution to this problem. We used a complex synthetic protein mixture to te
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Systems Metabolic Engineering,f various bioproducts, production of novel products, and broadening the substrate utilization range. Traditional metabolic engineering has been performed by manipulating a handful of genes and pathways based on known literature information and our rational thinking. Advances in omics technology, com
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Protein Function Prediction Based on Patterns in Biological Networks,ns of proteins. More specifically, we first detect patterns that appear in the neighborhood of proteins with a particular functionality, and then transfer annotations between two proteins only if they have similar annotation patterns. We show that, in comparison with other techniques, our approach p
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